45th Annual Meeting of the International Society for Gravitational Physiology
German Sport University, Cologne, Germany, 25-29 May 2026
Sunday, May 24
18:00 - 21:00
Informal Welcome + Registration
Sunday, May 24 | Main Building
Monday, May 25
08:00 - 08:30
Registration
Monday, May 25 | Main Building
09:00 - 09:30
Opening Ceremony
Monday, May 25 | EARTH
09:30 - 11:00
PLENARY #1 CURRENT CONCEPTS
Monday, May 25 | EARTH
Chair/s: Marc-Antoine Custaud, Ana Diaz Artiles
09:30
Trichoplax: Using the simplest animal to understand the impact of gravity and space on animal biology and human health
Patrick Humbert, La Trobe University
10:00
From Vascular Senescence to Regeneration: Can Microgravity Be a New Player in Endothelial Aging?
David Smadja, PARCC, INSERM, Université Paris Cité
11:00 - 11:30
Coffee Break
Monday, May 25 | Main Building
11:30 - 12:30
Young Investigator Contest #1
Monday, May 25 | EARTH
Chair/s: Nolan Herssens, Anna-Maria Liphardt
11:30
PHYSICAL ACTIVITY CHANGE AND TYPE II COLLAGEN EXCRETION DURING BED REST (BRACE)
Ines Ebner, (Department of Internal Medicine 3 - Rheumatology & Immunology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, Germany; Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, Germany)
11:45
Gravity Sensing in 3D: Cytoskeletal Gene Regulation in Breast Cancer Spheroids
Jose Luis Cortes Sanchez, (Institute of Anatomy, Faculty of Medicine, Otto von Guericke University Magdeburg, Germany.)
12:00
Artificial Gravity Preserves Resting Metabolic Rate in a 60-Day Bed Rest Model
Saul Martin Rodriguez, (Karolinska Institutet)
12:15
Cerebral Autoregulation During Valsalva Maneuver is Preserved During Spaceflight
Surat Kulapatana, (1 Vanderbilt University Medical Center, Department of Medicine, Division of Genetic Medicine and Clinical Pharmacology, Vanderbilt Autonomic Dysfunction Center, Nashville TN, USA
2 Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA
3 Siriraj Vascular Research Center, Department of Physiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand)
12:30 - 13:00
Lunch Break
Monday, May 25 | Cafeteria
13:00 - 14:00
Poster Session #1
Monday, May 25 | EARTH / Stage
Upper-Limb Sensorimotor Function in Altered Gravity Environments
Tatiana Maillard, (University of Fribourg, Control and Perception Laboratory)
Mouse brain adaptive responses to hypergravity 2g-exposure
David Dubayle, (université Paris Cité)
ΜIMMUNE – A microfluidic real-time immune monitoring assay for spaceflight
Marina Cara Tuschen, (Laboratory of Translational Research ‘Stress and Immunity’, Department of Anesthesiology, LMU Hospital, Ludwig-Maximilians-Universität, Munich, Germany)
Continuous physiological monitoring during the Race Across America (RAAM)
Leon Fesseler, (Charité - Universitätsmedizin Berlin)
Naturally Derived Supplements and Microgravity-induced Mitochondrial Stress
Christopher Conway, (Carroll College)
Autonomic and Hemodynamic Responses to Posture and Sensory Conflict in VR
Malik Nasir Afzal Khan, (Center for Spaceflight and Aviation Health, College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates)
A validated model to study the cardiac response to lower body negative pressure
Francesco Tripoli, (Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy)
Camera Number Effects on Markerless Motion Capture Accuracy during E4D-Exercise
Ida Nørgaard, (Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark), et al.
Coupling In-Vitro Hemodynamics With In-Vivo Autoregulation in Variable Gravity
Cyril Mani, (Medical Student, McGill University
Faculty of Health Sciences)
Using Organoids to Study Tissue and Cellular Responses to Spaceflight Conditions
Sarah Schunk, (Institute of Aerospace Medicine, Applied Aerospace Biology, German Aerospace Center (DLR))
Cardiovascular Effects of Hypercapnia During LBNP and Head-Up Tilt
Rocco Skert, (King's College London)
Left ventricular papillary muscle atrophy in a bed rest model of weightlessness
Cyril Tordeur, (Laboratory of Physics and Physiology, Université libre de Bruxelles (ULB), Brussels, Belgium)
Edge Intelligence for Sensor-Driven Physiological Health in Space Ops & Research
Mike Crooks, (Right Step / Taltech)
Chronic exposure of crickets to simulated hypergravity
Sophie Kasdorf, (Department of Biology, Carleton University, Ottawa, Canada)
Can Kinesiology tape reduce falls risk on the Moon: a pilot study.
Kirsty Lindsay, (Aerospace Medicine and Rehabilitation Laboratory, School of Sport, Exercise and Rehabilitation, Northumbria University, Newcastle UK.)
Gravity-Dependent Responses and Reactivity in Astrocytes
Brenda Dihlmann, (Department of Applied Aerospace Biology, Institute of Aerospace Medicine, German Aerospace Center, Cologne, Germany)
Multi-Omic Profiling of Extreme Phenotypes to Enhance Astronaut Health
Anurag Sakharkar, (Dr. Christopher E. Mason lab, Weill Cornell Medicine)
Validation of Point-of-Care Diagnostics for Spaceflight
Katharina Biere, (Laboratory of Translational Research ‘Stress and Immunity’, Department of Anesthesiology, LMU Hospital, Ludwig-Maximilians-University Munich, Munich, Germany)
NIRS: Leg blood pooling during tilt test in Dry Immersion and Head-down Bed Rest
Roman Zhedyaev, (IBMP RAS, Moscow, Russia)
Hypercoagulability In Spaceflight: Divergent Mechanisms Between The Sexes?
Polly Jarman, (Simon Fraser University)
14:00 - 15:30
Exploration Focused Science #1 - Muscoloskeletal
Monday, May 25 | EARTH
Chair/s: Franzisca Kopanev, Kirsty Lindsay
14:00
Microgravity deregulates the BAG3 muscle maintenance system
Jörg Höhfeld, (University of Bonn, Cell Biology,
Bonn, Germany)
14:15
Application of musculoskeletal organ-chip technology in microgravity research
Frank Schulze, (Center for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald)
14:30
Preliminary results of 12-weeks progressive resistance training on a centrifuge
Timo Frett, (Institute of Aerospace Medicine, German Aerospace Center (DLR))
14:45
Crewmember perceptions of BFR exercise in orbit on SpaceX Fram2 mission
Claire Bruce-Martin, (Northumbria University)
15:00
MOGOS – Enabling astronaut training and research in simulated reduced gravity
Tom Hoppenbrouwers, (Space Applications Services NV/SA)
15:15
Changes in spinal protrusions and scoliotic curvatures during Dry Immersion
Ilya Rukavishnikov, (RF SSC- IBMP RAS)
14:00 - 15:30
Neurology +
Monday, May 25 | MOON
Chair/s: Diana Giraldo, Brandon Macias
14:00
Ophthalmological changes following 10-day HDBR vs. 10-day DI
Marc Kermorgant, (Department of Neurology, University Hospital of Toulouse, Toulouse, France)
14:15
Effects of Altered Gravity on Human iPSC-Derived Motor Neurons
Sarah Schunk, (Institute of Aerospace Medicine, Applied Aerospace Biology, German Aerospace Center (DLR))
14:30
Bridging space and clinic: ocular morphometrics in SANS and IIH
Ge Tang, (Institute for Neuroradiology, University Hospital, LMU Munich, Munich, Germany)
14:45
Claudin Alterations and Junction Remodeling in Intestinal Cells in Mars Gravity
Chiara Bertini, (Department of Physics, University of Trento, Trento, Italy - Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy)
15:00
Functional Characterization of Retinal Organoids Under Altered Gravity
Rouhollah Habibey, (Eye Clinic and Polyclinic, University Hospital Bonn, University of Bonn, Ernst-Abbe-Str. 2, D-53127 Bonn, Germany.)
14:00 - 15:30
ISS #3 - Specials
Monday, May 25 | MARS
Chair/s: Yannick Lichterfeld, Oliver Opatz
14:00
Glucose tolerance onboard ISS: results from an Oral Glucose Tolerance Test
Martina Heer, (IU International University of Applied Sciences & Institute of Nutritional Sciences, University of Bonn, Germany), et al.
14:15
Mapping changes in ocular tissue strain upon spaceflight using OCT time series
Santiago Costantino, (University of Montreal)
14:30
Beyond Light in Space: Social Zeitgebers Shape Core Temperature Rhythms
Alexander Stahn, (Charité – Universitätsmedizin Berlin, Center for Space Medicine and Extreme Environments)
14:45
Artificial weight loading in space flight and neuroplasticity of the brain
Elena Fomina, (Institute for Biomedical Problems, Russian Academy of Sciences)
15:00
WOUND HEALING AND STRATEGIES FOR TISSUE REGENERATION IN SPACE
Monica Monici, (ASAcampus JL, ASA Res. Div., DSBSC, University of Florence)
15:15
EasyMotion-2:EMS as a spaceflight and clinical countermeasure to muscle atrophy
Viktor Heinz, (Charité Universitätsmedizin Berlin)
15:30 - 16:00
Coffee Break
Monday, May 25 | Main Building
16:00 - 17:30
ISS #1 - Neurology
Monday, May 25 | EARTH
Chair/s: Jean-Luc Morel, Ge Tang
Live-Cell Imaging of Astrocyte Reactivity under Space Conditions using FLUMIAS
Yannick Lichterfeld, (Department of Applied Aerospace Biology, Institute of Aerospace Medicine, German Aerospace Center (DLR))
Lost in Space? New Insights from the CIPHER Spatial Cognition Experiment
INTERNAL JUGULAR VEIN RESPONSE TO 10-DAY DRY IMMERSION AND HEAD-DOWN BEDREST
Adrien Robin, (Aerospace and Extreme Environment Nursing Program, College of Nursing, Texas A&M University, Bryan, Texas, USA)
16:45
Metabolic and muscle deconditioning after 10 days of dry immersion vs bed rest
Matthieu Marty, (Institute of Metabolic and Cardiovascular Diseases, Inserm/UT UMR1297, University of Toulouse, France)
17:00
Vivaldi 3: Evaluation of muscle deconditioning in bed rest and dry immersion
Julian Theuil, (DMEM, Université de Montpellier, INRAE, Montpellier, France.
PhyMedExp, CNRS, INSERM, University of Montpellier, F34295 Montpellier, France.)
17:15
VIVALDI 3: single myofiber contractile properties after dry immersion or bed rest
Margot Issertine, (University of Montpellier), et al.
17:30
Comparative Effects of Dry Immersion and Bed Rest on Cartilage Biomarkers
Maren Dreiner, (Institute of Biomechanics and Orthopaedics, German Sport University Cologne, Köln, Germany)
17:45
Immune states during Dry Immersion and Bed Rest - Results from VIVALDI III
Dominique Moser, (Laboratory of Translational Research ‘Stress and Immunity’, Department of Anesthesiology, LMU Hospital, Ludwig-Maximilian-University, Munich, Germany)
16:00 - 17:30
Surprise Bag
Monday, May 25 | MARS
Chair/s: Timo Frett, Dominique Moser
16:00
Characterizing spaceflight-induced hepatic steatosis in vitro and in vivo
Ben Cools, (Department of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, Brussels, Belgium;
Nuclear Medical Applications Institute, Belgian Nuclear Research Centre, Mol, Belgium.)
16:30
Extracellular vesicle responses to space flight associated stressors
Amirmohammad Nasiri Kenari, (Research Center for Advanced Science and Technology (RCAST), The University of Tokyo, Tokyo, Japan
La Trobe Institute for Molecular Science (LIMS), La Trobe University, Melbourne, Australia)
16:45
Force sensing ion channels regulate cellular adaptations to microgravity
Kate Poole, (University of New South Wales)
17:00
Mice sperm after short-term simulation weightlessness and 2g-hypergravity
Irina V. Ogneva, (1- SSC RF Institute of Biomedical Problems RAS
2- Yu.A. Gagarin Research and Test Cosmonaut Training Center
3-Sechenov University)
17:15
Iron metabolism links blood and skeletal responses to simulated microgravity
Emily Akerman, (INSERM U1059 SAINBIOSE, University of St Etienne, Mines St Etienne, FRANCE)
20:30 - 23:00
Welcome Reception
Monday, May 25 | NENI Cologne
Tuesday, May 26
07:00 - 08:30
Early Bird Exercise
Tuesday, May 26 | Entrance Swimming Pool GSU
08:00 - 08:30
Registration
Tuesday, May 26 | Main Building
09:30 - 11:00
PLENARY #2 THE FUTURE OF SPACEFLIGHT - Where do we go from here?
Together with ambassadors from international space agencies, representatives from science and industry as well as current and past astronauts, current developments in spaceflight will be targeted and discussed. A specific focus will be on the involvement of the private sector, and the potential role of agencies and science in this context.
Tuesday, May 26 | EARTH
Chair/s: Constance Badali, Stefan Schneider
09:30
Introduction
10:00
Interactive Discussion
Panel members (so far): Michaela Girgenrath (DLR), Angelique van Ombergen (ESA), Meghan Everett (VAST), Victor Maier (The Exploration Company), Rodrigo Fernandez-Gonzalo (Karolinska), Floris Wuyts (Antwerp University), Reinhold Ewald (former Astronaut) and John McFall (Astronaut Reserve)
BRACE: Cycling and artificial gravity impact during bed rest on subchondral bone
Mathilde Lepileur, (Department of Internal Medicine 3 – Rheumatology & Immunology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, Germany
Deutsches Zentrum Immuntherapie (DZI), FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Germany)
11:45
Brain Changes in Response to Isolation and Confinement
Lara Zimmermann, (Charité Universitätsmedizin Berlin, Institute of Physiology, Center for Space Medicine and Extreme Environment Berlin, Berlin, Germany)
12:00
Reduced Myocardial Extracellular Matrix Hydration in Microgravity: T2 Radiomics
Francesca Righetti, (Politecnico di Milano University, Department of Electronics Information and Bioengineering (Milan, Italy))
12:15
Evaluation of Ventilatory Thresholds during Exercise in Simulated Hypogravity
Catherine Taylor, (Aerospace Physiology Laboratory, Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, BC, Canada)
Earthgazing to Enhance Affective Experience During An 8-Months Isolation Study
Noah Miller, (Simon Fraser University - Canada)
Social Isolation Effects on Autonomic, Immune, Sleep & Cognition: The Island Study
Costanza Scatà, (Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.)
What happens to brain ventricles with repeated long-duration spaceflight?
Diana L. Giraldo, (University of Antwerp)
Onset and Time Course of Anabolic Resistance During Experimental Bed Rest
Teresa Cannito, (University of Trieste)
Neurophysiological Signatures of Affect in Response to an Earthgazing Experience
Roswitha Duwenbeck, (Fakultät für Ingenieurwissenschaften, Universität Duisburg-Essen, Germany)
Autonomic–Bone Interactions During Gravitational Unloading: The DAYSTAR Project
Greta Salafia, (Department of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.), et al.
Gait parameters after the first and second weeks of 14-day Dry Immersion
Elena Tomilovskaya, (Institute of Biomedical Problems of the Russian Academy of Sciences)
Physical Demands of Flywheel Exercise during Parabolic Microgravity Flights
Étienne Chassé, (1. Human performance Research and Development, Canadian Morale and Welfare Services, Ottawa, Canada)
Autonomic and Metabolic Adaptations to Microgravity Analog: DAYSTAR Project
Francesca Magna, (Department of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.)
AutonomicSystem for searching muscle-heart-brain axis in microgravity conditions
Lucia Silvia Giobbi, (Department of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy)
BiMU – Core-Shell 3D Bioprinting of Motoric Units
Gabor Trautmann, (Charité Berlin)
Dynamic Functional Connectivity Alterations after Long-Duration Spaceflight
Sepehr Mortaheb, (University of Antwerp)
Defining preload during orthostatic stress: Impedance versus Echocardiography
Victorien Faivre-Rampant, (Normandie Univ, Inserm Comete, GIP Cyceron, CHU Caen Normandie, 14000 Caen, France
Department of Automatics, Biocybernetics, and Robotics, Jozef Stefan Institute, Ljubljana, Slovenia
Jozef Stefan International Postgraduate School, Ljubljana, Slovenia)
Spaceflight Effects on the Mandible and Temporomandibular Disorders
Maria Benduch, (Jagiellonian University Medical College
Doctoral School of Medical and Health Sciences
Kraków, Poland)
Jumping on the Moon as a Potential Cardiovascular Exercise Countermeasure
Patrick Swain, (1 Aerospace Medicine and Rehabilitation Laboratory, School of Sport, Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, United Kingdom)
Hypogravity Simulation using the Variable Gravity Suspension System
Patrick Swain, (1 Aerospace Medicine and Rehabilitation Laboratory, School of Sport, Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, United Kingdom)
Exercise Countermeasures in Spaceflight: Systematic Review and Proposal
CARLOS MUÑOZ MOYANO, (SPACEMED)
E-Noses as Companions for remote environments: Surgical Risk Prediction
Gender differences in disuse-induced insulin resistance
Alja Ivetac, (University of Trieste)
. Gut Microbiota in Microgravity-Induced Cardiovascular and Muscle Deconditioning
Zeinab Ibrahim, (Postdoctoral Research Fellow
•
Center for Space and Aviation Health)
14:00 - 15:30
Exploration Focused Science #2 - Other
Tuesday, May 26 | EARTH
Chair/s: Floris Wuyts, Ines Ebner
14:00
First Suited Physiology Tests in LUNA: Feasibility and Outlook
Jan Breuer, (1 Institute of Aerospace Medicine, German Aerospace Center, Cologne, Germany
2 Institute of Biomechanics and Orthopaedics, German Sports University, Cologne, Germany)
14:15
Impact of Simulated Microgravity in Short-term Evolution of an RNA Bacteriophage
Alicia Rodríguez Moreno, (Center for Astrobiology (CAB) (CSIC-INTA))
14:30
Hindlimb suspension of male mice influences on pronuclei migration after IVF
Ksenia K. Gogichaeva, (1- SSC RF Institute of Biomedical Problems RAS)
14:45
Edible Insects and Microgravity: Implications for Space Exploration
Roberto Guidetti, (University of Modena and Reggio Emilia, Italy)
15:00
Reproductive Outcomes of Drosophila melanogaster under altered gravity conditions
Julsana Jalal, (Indian Institute of Space Science and Technology)
15:15
Translating Spaceflight Neuroimaging Findings to Mal de Débarquement Syndrome
Anna Finazzi Agrò, (University of Trento
University of Antwerp (Lab for Equilibrium Investigations and Aerospace, LEIA))
14:00 - 15:30
ISS #2 - Muscle & Heart
Tuesday, May 26 | MOON
Chair/s: Federico D'Amico, Saul Martin Rodriguez
14:00
DNA epigenetic changes are key endothelial cell adaptation to spaceflight.
Debora Angeloni, (The Institute of Biorobotics, Scuola Superiore Sant'Anna, Pisa, Italy)
14:15
Evaluation of room temperature-based preservation of 3D cardiac organoids
Cynthia Van Rompay, (Nuclear Medical Applications, Radiobiology Unit, SCK CEN, 2400 Mol, Belgium
Department of Biosystems, Mechatronics, Biostatistics and Sensors (MeBioS), Biomimetics group, KU Leuven, 3001 Leuven, Belgium)
14:30
Effects of NMES on human muscle health in short- and long-duration spaceflight
Alessandra Bosutti, (Department of Life Sciences, University of Trieste, Trieste, Italy)
14:45
Effects of NMES during short and long-term spaceflight on muscle perfusion
Bergita Ganse, (Saarland University, Werner Siemens Foundation Endowed Chair for Innovative Implant Development, Homburg, Germany)
15:00
Long-term spaceflight alters cardiorespiratory and cardio-postural interactions
Andrew Blaber, (Simon Fraser University)
15:30 - 16:00
Coffee Break
Tuesday, May 26 | Main Building
16:00 - 17:30
EDUCATION
The participation of 114 students in this year’s ISGP highlights the growing interest in space life sciences and reflects the strong future of this field.
During this educational session, we provide a platform for European institutions offering Bachelor’s and Master’s degree programs in space life sciences. These include the University of Bordeaux, the International Space University, and the SPACEMED Master’s, an Erasmus Mundus Joint Master’s program coordinated by the University of Caen in collaboration with the Charité Universitätsmedizin Berlin and the Jožef Stefan International Postgraduate School in Ljubljana.
As a special highlight, current SPACEMD master's students will pitch their ideas for their master's theses and aim to attract supervisors. Dive into the future of space life sciences, discover the research ideas of tomorrow, and perhaps meet your next student researcher.
Cap-Biospace, an educational program to support human space exploration
Alice Nicole, Université de Bordeaux
16:08
International Space University
Virginia Wotring, International Space University
16:16
SPACEMED - Erasmus Mundus Joint Master Degree on Physiology and Medicine of Humans in Space and Extreme Environments
Alexander Stahn, SPACEMED
16:26
Lift-Off Lab: The Master’s Pitch
Master students
18:00 - 23:00
Young Investigator Event
Tuesday, May 26 | PLAYA Cologne
Wednesday, May 27
07:00 - 08:30
Early Bird Exercise
Wednesday, May 27 | Entrance Swimming Pool GSU
09:30 - 11:00
PLENARY #3 OMICS
Wednesday, May 27 | EARTH
Chair/s: Constance Badali, Alexander Choukér
09:30
Multi-omics dynamics of human spaceflight
JangKeun Kim, Weill Cornell Medicine
10:00
Using AI in Astronaut Databases for Astronaut Health and Personalized Medicine
Nandu Goswami, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai
11:00 - 11:30
Coffee Break
Wednesday, May 27 | Main Building
11:30 - 12:30
Young Investigator Contest #3
Wednesday, May 27 | EARTH
Chair/s: Marc-Antoine Custaud, Katrin Stang
11:30
Exercise effect on energy intake and appetite during bedrest: The BRACE Study
Philippe St-Martin, (1) Faculty of Physical Activity Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.
2) Research Centre on Aging, Sherbrooke Geriatric Institute, Université de Sherbrooke, Sherbrooke, QC, Canada.
3) Université de Strasbourg, CNRS, IPHC UMR 7178, Strasbourg, France.)
11:45
When Microgravity Changes the Brain: The Need to Account For Brain Shifts
Hanna Mourguès, (Charité - Universitätsmedizin Berlin
Institute of Physiology, Center for Space Medicine and Extreme Environment Berlin, Berlin, Germany)
12:00
VIVALDI: SEX-SPECIFIC sTIMP-1 & sTIMP-2 LEVELS REACTING TO A 5-DAY DRY IMMERSION
Miriam Weyers, (Institute of Biomechanics and Orthopaedics, German Sport University Cologne, Cologne, Germany)
12:15
The temporal dynamics of standing balance in short-term spaceflight
Adéla KOLA, (Université de Caen Normandie, INSERM, COMETE U1075, CYCERON, CHU de Caen, Caen, France.)
12:30 - 13:00
Lunch Break
Wednesday, May 27 | Cafeteria
13:00 - 14:00
Poster Session #3
Wednesday, May 27 | EARTH / Stage
EFFECTS OF ISOLATION AND CONFINEMENT IN EXTREME ENVIRONMENTS
Monica Monici, (ASAcampus, ASA Res. Div., DSBSC, University of Florence)
Bed rest induced muscle loss leads to renal water loss and blood pressure rise
Xuemi Peng, (Amsterdam UMC, University of Amsterdam, Department of Nephrology, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Amsterdam Cardiovascular Sciences, Diabetes and Hypertensive Diseases, Amsterdam, The Netherlands.)
Autonomous Perfused Incubator for Endothelial Cell Studies in Variable Gravity
Max Jacolot, (Research Assistant, McGill University Department of Mechanical Engineering)
Changes in corticospinal and spinal excitability during 14-day Dry Immersion
Tatiana Shigueva, (Russia, Moscow, SSC RF – Institute of Biomedical Problems of RAS)
Cardiac remodeling in 60-day hypoxic HDT with RVE and artificial gravity (BRAVE)
Nikolas Lehmann, (DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, 17475 Greifswald, Germany)
Brain Microstructural Adaptation in Response to Long-Term Head-Down Tilt Bed Rest
Katharina Brauns, (Charité - Universitätsmedizin Berlin, Institute of Physiology, Center for Space Medicine and
Extreme Environment Berlin, Berlin, Germany)
Ground-based analogues comparing age & sex to spaceflight: a systematic review.
Jack van Loon, (VU University Amsterdam / ESA-ESTEC-TEC-MMG)
The Neural Basis of Operational Performance: An fMRI Study
Clemens Mundry, (Institute of Physiology, Charité – Universitätsmedizin Berlin, Berlin, Germany)
Effect of dry immersion vs bedrest on energy metabolism - The VIVALDI III study
Baptiste Chambrey, (University of Strasbourg, CNRS, IPHC UMR 7178, Strasbourg, France)
Gravity-Sensitive Regulation of P53-Mediated Cellular Stress Pathways
Avantika Upadhyay, (Barts and The London School of Medicine and Dentistry,
Queen Mary University of London, UK)
A Randomized Manikin Study On Cricothyrotomy in Simulated Microgravity
Konstantinos Vergos, (Radboud UMC)
Hormonal Contraceptives in Space: Thrombotic Risk and Pharmacokinetic Uncertainty
Alice Decaminada, (University of Caen)
Vestibular Contributions to Executive Function: A Systematic Review
Nico Fabian, (SpaceMed)
Systemic and skeletal muscle metabolic and transcriptomic remodeling in HDT
Jens Fielitz, (DZHK (German Center for Cardiovascular Research), Partner Site Nord, Greifswald, Germany)
Remodeling of cardiac structure and function in 60-day HDT and recovery
Jens Fielitz, (DZHK (German Center for Cardiovascular Research), Partner Site Nord, Greifswald, Germany)
Artificial gravity and exercise limit metabolic deconditioning in 60-day bedrest
Jean-Baptiste Chettouche, (Institute of Metabolic and Cardiovascular Diseases, INSERM/UT UMR1297, University of Toulouse, France)
NEMUCO: A 3D Nerve–Muscle Model to Study NMJ Vulnerability to Microgravity
Gaia Ziraldo, (Charité - Universitätsmedizin Berlin, Institute of Integrative Neuroanatomy, Berlin, Germany)
Physiological advantages and challenges of possible adolescent astronauts
Matilda Jaschinski, (International School Delft)
Peripheral skin cooling during gravitational challenges in parabolic flight
Oliver Opatz, (Charité Universitätsmedizin Berlin)
Continuous Thermal Monitoring in Space using a Miniaturized Sensor (Thermo-Mini)
Oliver Opatz, (Charité Universitätsmedizin Berlin)
Does Spaceflight Accelerate Ventricular Expansion? Long-Term Evidence
Diana L. Giraldo, (University of Antwerp)
Altered Gravity: Challenges and Benefits - A Clinician’s Perspective
Christian Lüthen, (ErasmusMC - Thorax Center - Dept. of Cardiothoracic Anesthesiology)
Artificial Gravity: From Theory to Operational Reality
Donald E. Watenpaugh, (Department of Bioengineering
University of Texas at Arlington
Arlington, Texas
USA
and
Department of Physiology and Anatomy
University of North Texas Health Science Center
Fort Worth, Texas
USA)
SPACEMED-Mechanical Unloading as a Systemic Stressor in Spaceflight
Pedro Garza, (Charité – Universitätsmedizin Berlin)
SPACEMED Radiation-Induced Y Chromosome Aberrations in Mouse Macrophages InVitro
Joseph Carol, (University of Virginia)
14:00 - 15:30
BedRest #1 - Muscoloskeletal
Wednesday, May 27 | EARTH
Chair/s: Ana Diaz Artiles, Mirko Mandic
14:00
Effects of 6° head-down BR model on FNDC5/Irisin and load-sensitive proteins
Onofrio Daniele Terrevoli, (Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy)
14:15
Bed Rest Accurately Mimics Spaceflight-induced Musculoskeletal Variability
Jonas Böcker, (Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany)
14:30
Can artificial gravity mitigate microgravity-induced bone deconditioning?
Franzisca Kopanev, (Charité Universitätsmedizin Berlin, Center for Muscle and Bone Research)
14:45
Metabolic Response of Skeletal Muscle during Long-Term Head-Down Tilt Bed Rest
Michael Boschmann, (1Clinical Research Unit (CRU) at the Experimental & Clinical Research Center (ECRC) – a joint collaboration Charité-Universitätsmedizin Berlin, Max Delbrück Center (MDC) for Molecular Medicine in the Helmholtz Association, Berlin, Germany)
15:00
Adaptive Electrostimulation Against Musculoskeletal Decay: a Bed Rest Campaign
Freya Beyne, (REA S.r.l.)
15:15
Effects of equal duration Dry Immersion and Head-Down Bed Rest on human body
Elena Tomilovskaya, (RF SSC - Institute of Biomedical Problems RAS)
14:00 - 15:30
Isolation
Wednesday, May 27 | MOON
Chair/s: Judith-Irina Buchheim, Monica Monici
14:00
Eight Months of Isolation Alter Hippocampal Subfields in a Spaceflight Analog
Clemens D. Mundry, (Charité - Universitätsmedizin Berlin, Institute of Physiology, Center for Space Medicine and
Extreme Environment Berlin, Berlin, Germany)
14:15
Microstructural Brain Changes Following 8 Months of Isolation and Confinement
Katharina Brauns, (Charité - Universitätsmedizin Berlin, Institute of Physiology, Center for Space Medicine and Extreme Environment Berlin, Berlin, Germany)
14:30
Grid cell-like representations in the entorhinal cortex after prolonged isolation
Julius Schaut, (Charité - Universitätsmedizin Berlin, Institute of Physiology, Center for Space Medicine and
Extreme Environment Berlin, Berlin, Germany)
14:45
I-CELLated Brains: Deciphering Neurobehavioural Changes in Response to Isolation
Lail Edelsztein, (Center for Space Medicine & Extreme Environments Berlin, Charité – Universitätsmedizin Berlin, Germany)
15:00
Frozen in Time but Aging Faster-Accelerated Brain Age in Antarctic Expeditioners
Lara Zimmermann, (1Charité - Universitätsmedizin Berlin, Institute of Physiology, Center for Space Medicine and Extreme Environments Berlin, Berlin, Germany)
15:15
Impact of Gravity on early development and reproduction
Dominique Luton, (APHP Univ Paris Saclay)
15:30 - 16:00
Coffee Break
Wednesday, May 27 | Main Building
16:00 - 17:30
Hand-Picked Specials
Wednesday, May 27 | EARTH
Chair/s: Rebecca Billette de Villemeur, Maren Dreiner
16:00
Effects of countermeasures on ophthalmological changes after a 60-day HDBR
Marc Kermorgant, (Department of Neurology, University Hospital of Toulouse, Toulouse, France)
16:15
Recent and remote olfactive associative memory are not impaired by hypergravity
Jean-Luc Morel, (INCIA, UMR5287, CNRS, University Bordeaux)
16:30
Microgravity-Induced Alterations in human B cell function
Alamelu Sundaresan, (Texas Southern University)
16:45
HIDRA-OMICS: From a Drop of Blood to Plasma Proteome Using Space-Compatible DBS
Karen Barchetti, (Université Paris Cité, INSERM, PARCC Paris Cardiovascular Research Centre, Paris, France.)
17:00
Glucose metabolism in head‑down bed rest and mechanical countermeasures
Martina Heer, (IU International University of Applied Sciences, Erfurt, Germany; Institute of Nutritional Sciences University of Bonn, Germany)
17:15
Planarians as an Animal Model for Space-Related Pharmacology Experiments
Virginia Wotring, (International Space University)
16:00 - 17:30
Muscoloskeletal #1
Wednesday, May 27 | MOON
Chair/s: Jens Fielitz, Tatiana Maillard
16:00
Effects of Simulated Microgravity on Muscle Progenitor Cell Biology
Mariana Vinagre, (Leiden University Medical Center (LUMC), European Space Agency (ESA))
16:15
Acute Cardiorespiratory Responses During Locomotion in Simulated Lunar Gravity
Bradley Barbour, (Northumbria University)
16:30
Systemic-Oral-Microbiota-Brain-Axis
Dirk Neefs, (Department of Biomedical Surgical and Dental Sciences
Dental School Università degli Studi di Milano, Italy), et al.
16:45
Synergies between spaceflight research, bone healing models and digital twins
Andreas Arnegger, (OSORA medical GmbH)
17:00
Combined countermeasures against simulated micro- and lunar-gravity muscle loss
Margot Issertine, (DMEM, Univ Montpellier, INRAE, Montpellier, France
PhyMedExp INSERM, Centre National de la Recherche Scientifique, Université de Montpellier, CHRU Montpellier, Montpellier, France)
17:15
Simulated Microgravity Affects Distinct Populations of Meniscus Cells Differently
Adetola Adesida, (University of Alberta)
18:00 - 24:00
Gala Dinner
Wednesday, May 27 | German Sport and Olympia Museum Cologne
Thursday, May 28
07:00 - 08:30
Early Bird Exercise
Thursday, May 28 | Entrance Swimming Pool GSU
09:30 - 11:00
PLENARY #4 PHARMACOLOGY IN SPACE
This plenary session marks the official launch of the ISGP Aerospace Pharmacy and Pharmacology Group subcommittee (APPG). Bringing together astropharmacists, academic researchers, and a flight surgeon, this session will explore the critical gaps and challenges facing space pharmacology today. Through a dynamic, interactive discussion panel, particular emphasis will be placed on bridging research and operational practice, with the aim of collaboratively developing concrete and actionable solutions.
Thursday, May 28 | EARTH
Chair/s: Karen Barchetti, Audrey Derobertmasure, Li Shean Toh
09:30
Introduction to Aerospace Pharmacy and Pharmacology Group
Li Shean Toh, Monash University
09:40
Microsampling approaches for Space Pharmacology research
Audrey Derobertmasure, Greater Paris University Hospitals (AP-HP), Université Paris Cité, INSERM
09:50
Spaceflight Drug Usage: Insights from Astronauts and Space Tourists
Karen Barchetti, Université Paris Cité, INSERM, PARCC - Paris Cardiovascular Research Center, Paris, France
10:00
SEREN — Space Life Sciences European Research Network
Willian Abraham da Silveira, University of Salford
10:10
Interactive Discussion Panel
Panelists: Pr. Phil Williams, Dr. Virginia Wotring, Dr. Ben Cools, Pr. Li Shean Toh, Dr. Audrey Detobertmasure, Dr. Karen Barchetti, Pr. Willian Da Silveira.
11:00 - 11:30
Coffee Break
Thursday, May 28 | Main Building
11:30 - 13:30
BRACE & BRAVE
Thursday, May 28 | EARTH
Chair/s: Constance Badali, Ana Diaz Artiles
11:30
Effects of bed rest on brain microstructure: results from BRACE
Diana L. Giraldo, (University of Antwerp), et al.
11:45
Cortical responses to bed rest with countermeasures: BRACE findings
Diana L. Giraldo, (University of Antwerp)
12:00
Salt happens: Dietary intake and fluid regulation in head-down bed rest, BRACE
Carol Bryans, (1Schlegel-University of Waterloo Research Institute for Aging, Waterloo, Canada
2Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, Canada)
12:15
Same vein, different story: Jugular flow differs by Doppler gate location, BRACE
Carol Bryans, (1Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, Canada)
12:30
Vibration & resistance exercise prevent bed rest-induced muscle fat infiltration
Rodrigo Fernandez-Gonzalo, (Karolinska Institutet, Stockholm, Sweden)
12:45
Effects of bed rest on lumbar neuromuscular control
Enrico De Martino, (Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark), et al.
13:00
Changes in lumbar muscle fat fraction during bed rest
Enrico De Martino, (Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark), et al.
13:15
Brain Perfusion in 60-Day Bed Rest: Impact of Artificial Gravity and Exercise
Nadja Bastiaens, (Center for Space Medicine & Extreme Environments Berlin, Charité – Universitätsmedizin Berlin)
13:30
Limited effects of countermeasures on bone loss in microgravity: the BRACE study
Lower Body Negative Pressure Effects on Jugular Hemodynamics in Parabolic Flight
Huc Pentinat-Llurba, (Texas A&M University, USA)
12:45
Effects of acute microgravity on flow complexity in the internal jugular vein
Roxy Fournier, (University of Waterloo)
13:00
Cardio-Postural Interactions During Parabolic Flight: A Pilot Methods Study
Sandra Faragalla, (Simon Fraser University)
13:15
Cerebral blood velocity responses during altered g-levels
Timo Klein, (Institute of Sport Science, University of Rostock, Germany
Centre of Transdiciplinary Neurosciences, University Medical Center Rostock
Department Ageing of Individuals and Society,
Interdisciplinary Faculty, Univeristy of Rostock)
11:30 - 13:30
Cardiology & Immunology/Haematology
Thursday, May 28 | MARS
Chair/s: Victorien Faivre-Rampant, Mirko Mandic
11:30
Effects of simulated microgravity and partial gravity on human immune cells
Lukas Baden, (Laboratory of Translational Research ‘Stress and Immunity’, Department of Anesthesiology, LMU Hospital, Ludwig-Maximilian-University, Munich, Germany)
11:45
Unveiling arterial wave dynamics in altered gravity via cardiovascular modeling
Giovanna Colussi, (Department of Mechanical and Aerospace Engineering (DIMEAS), Politecnico di Torino, Turin, Italy)
12:00
CEPHALIC CARDIOVASCULAR AND OCULAR RESPONSE TO ALTERED GRAVITY IN HYPOVOLEMIA
Adrien Robin, (Aerospace and Extreme Environment Nursing Program, College of Nursing, Texas A&M University, Bryan, Texas, USA)
12:15
Papillary vs ventricular muscle: transcriptomic divergence under tail suspension
Cyril Tordeur, (Laboratory of Physics and Physiology, Université libre de Bruxelles (ULB), Brussels, Belgium)
12:30
Circadian Clock and Metabolic Gene Expression Changes During Bear Hibernation
Marina Wenn, (Laboratory of Translational Research ‘Stress and Immunity’, Department of Anesthesiology, LMU Hospital, Ludwig- Maximilian-University, Munich, Germany)
12:45
Drug Prediction for Immune Dysregulation from the Inspiration4 Mission
Anurag Sakharkar, (Dr. Christopher E. Mason lab, Weill Cornell Medicine)
13:00
Stress and Immune monitoring during the free-flyer Fram 2 mission (SpaceXposome)
Judith-Irina Buchheim, (Laboratory of Translational Research ‘Stress and Immunity’, Department of Anesthesiology, LMU Hospital, LMU Munich, Munich, Germany)
13:30 - 14:30
Lunch Break
Thursday, May 28 | Cafeteria
14:30 - 16:00
BedRest #2 - Cardiology
Thursday, May 28 | EARTH
Chair/s: Adam McDonnell, Cyril Tordeur
14:30
Daily LBNP-Training preserves vagal heart rate recovery after pre-syncope
Stefan Moestl, (DLR – Institute of Aerospace Medicine, Cologne)
14:45
Exercise during artificial gravity: How useful as a countermeasure in space?
Dag Linnarsson, (Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden)
15:00
Cardiac Autonomic and Repolarization Adaptations During Head-Down Tilt Bed Rest
Sarah Solbiati, (Politecnico di Milano, Department of Electronics, Information and Bioengineering)
15:15
Sex and baseline values influence blood volume changes during head-down bed rest
Jeremy Rabineau, (Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, Ontario, Canada; Université Paris Cité, INSERM, Paris Cardiovascular Research Centre – PARCC, Paris, France)
15:30
Unloading Gravity, Unveiling Resilience:Autonomic Responses to Bed Rest
Angelica Carandina, (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano)
15:45
Toward heart rate reference values for cardiovascular deconditioning